Sharpening odor perception may not be as powerful a finding as pairing a smell with an emotion, but it can, for example, improve your ability to describe the bouquet of a glass of wine. To my delight, such findings could justify tasting fine wines, dining on adventurous cuisine, even taking a trip to the Yankee Candle Company. Granule cells fine-tune odor messages from the nose before they are sent to higher processing centers of the brain.Ī study out of a prominent Parisian lab showed that enriching your odor environment might increase the lifespan of these new neurons and improve a person’s odor memory. The olfactory system is one of the few regions of the brain that produces new neurons, granule cells, in adulthood. While many forms of olfactory learning that are prominent in infancy wane with age, does that mean as we get older we cannot improve olfactory acumen to the level of a master sommelier? Mothers actively sculpt their future children’s odor discrimination abilities and their palates as a consequence. Those not exposed to anise in the womb ignored the anise odor or reacted negatively to it.
There is also scientific evidence that breast-fed infants develop preferences for their mother’s diet and that newborns prefer smells from their mother’s diet during pregnancy.įor example, babies of mothers who consumed anise during pregnancy were found to have a positive response to the odor of anise. My thesis work found that a possible critical period in linking a smell with a memory or emotion occurred in the first two weeks of a rat’s life, which translates roughly to the first year of a human’s life.
Such information could be highly relevant to the food and beverage industry, too. That understanding appealed to me as a budding foodie and wine enthusiast. That was great when I talked to my neuroscientist friends.īut what about everybody else? I could say I was trying to explain how the emotional circuits of the brain affect our perception of smell. Neuroscientists could understand that I was studying how the neuromodulator norepinephrine affects receptors in the olfactory circuit. So I launched a quest: What was the value of what I was learning? How could I explain the meaning of my work to the average taxpayer who, after all, was helping make my research possible? But I had apparently asked a clinically irrelevant question.Īll this effort for what? Was all my hard work simply adding to the Encyclopedia Galactica? I had chosen a great mentor and exciting scientific techniques. ( May, 2013) I was officially suffering from a mid-PhD crisis.Īfter years of working on my thesis, “norepinephrine-induced long-term modifications of rat olfactory bulb circuit dynamics,” I discovered my findings likely would never change the course of a disease. Strategic Infrastructure for Research Committee.Colorado Clinical & Translational Sciences Institute (CCTSI).Residents and Fellows as Educators Elective.In conclusion, the vae in stable-diffusion has (4096 * 32) / (256 * 14) >= 36x more information than the vqgan in dalle-mini to reconstruct the same image at the same resolution. stable-diffusion: (4x32x32), -> 4096 "tokens" in float (32 bits or 16 bits, depending on the precision).stable-diffusion: no restriction on resolution.dalle-mini: restricted to 256x256 resolution.Note: Comparison between VQGAN in dalle-mini and VAE in stable-diffusion fine-tune the unet diffusion model of stable-diffusion.So it still struggle to generate the latent of anime-styled images in detail. But I think it's because the unet diffusion model of stable-diffusion is not trained to generate anime-styled images.
FINETUNE ODOR CODE
This repository contains the code for fine-tuning the following models:įine-tuning VQGAN decoder of Craiyon (dalle-mini)
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